Associate Professor Scott Byrne is a teaching and research academic at the University of Sydney who leads a group devoted to studying the biological effects of sunlight exposure. He is an immunologist who has established an international reputation in the field of photomedicine. He has made numerous seminal contributions in this area, particularly his discovery that UV activates a unique type of regulatory B cell. Recently he demonstrated that UV-activated BRegs mediate sunlight protection from CNS-targeted autoimmune diseases. His group have now discovered that UV-activated B cells may be a promising new target for the treatment of skin cancer.